“Chemoinformatics in Drug Discovery” hosted at the National Laboratory in Genomics for Biodiversity (CINVESTAV UGA LANGEBIO) between October 15th and 18th, 2019 was a successful CABANA workshop. Twenty-four delegates from different regions of Latin America - Mexico, Colombia, Peru, Argentina and Cuba – attended the workshop and discovered Mexico’s heart. Our 5 speakers Dr. Jose Luis Medina Franco (from UNAM Mexico City), Dr. Fabien Plisson (from CINVESTAV UGA LANGEBIO, Irapuato), MSc. Rodrigo Ochoa (University of Antioquia, Colombia) as well as UNAM students MSc. Barbara Diaz and Edgar Lopez introduced the participants to theories and practices in computer-aided drug discovery – structure-based and ligand-based drug discovery. All classes were well received. The workshop opened new collaborations and possible projects between the represented institutions.